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Alexander Porfiryevich Borodin (12 November 1833 – 27 February 1887) was a Russian Romantic composer and chemist of Georgian–Russian parentage. He was one of the prominent 19th-century composers known as "The Five", a group dedicated to producing a "uniquely Russian" kind of classical music. Borodin is known best for his symphonies, his two string quartets, the symphonic poem In the Steppes of Central Asia and his opera Prince Igor. A doctor and chemist by profession and training, Borodin made important early contributions to organic chemistry. Although he is presently known better as a composer, he regarded medicine and science as his primary occupations, only practising music and composition in his spare time or when he was ill. As a chemist, Borodin is known best for his work concerning organic synthesis, including being among the first chemists to demonstrate nucleophilic substitution, as well as being the co-discoverer of the aldol reaction. Borodin was a promoter of education in Russia and founded the School of Medicine for Women in Saint Petersburg, where he taught until 1885. In the 1880s pressures of work and ill health left him little time for composition. He died suddenly in 1887 while at a ball.